Prescriber Uptake and Use of Novel Lipid‐Lowering Therapies

The majority of US clinicians prescribing LLT have never prescribed a PCSK9i or BA, and among those who do, most have used these therapies in only a few patients. However, there exist distinct groups of early adopters and high-volume users with higher approval rates, slightly more years in practice, and more cardiologists. Given that prescription approval rates for both PCSK9i and BA have now increased to >80% in our analysis, increasing uptake of novel LLT will require interventions to increase use among clinicians.

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Publication Details

Journal
Journal of the American Heart Association
Published
2025-05-02
DOI
https://doi.org/10.1161/jaha.125.040768
Citations
5
Primary Topic
Lipoproteins and Cardiovascular Health
Type
article
Field-Weighted Citation Impact
10.03
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article

Prescriber Uptake and Use of Novel Lipid‐Lowering Therapies

Evelyn Sarnes, Anand Gupta, Emily Decicco, Ann Marie Návar et al.
5 citations
Journal of the American Heart Association
Lipoproteins and Cardiovascular Health
10.03
article

Prescriber Uptake and Use of Novel Lipid‐Lowering Therapies

Evelyn Sarnes, Anand Gupta, Emily Decicco, Ann Marie Návar, Eric David Peterson, Jimin Hwang
article en
5 citations

Abstract

The majority of US clinicians prescribing LLT have never prescribed a PCSK9i or BA, and among those who do, most have used these therapies in only a few patients. However, there exist distinct groups of early adopters and high-volume users with higher approval rates, slightly more years in practice, and more cardiologists. Given that prescription approval rates for both PCSK9i and BA have now increased to >80% in our analysis, increasing uptake of novel LLT will require interventions to increase use among clinicians.

Journal of the American Heart AssociationVol. 14(9)
Esperion Therapeutics (United States) (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 2%
Lipoproteins and Cardiovascular Health
10.03
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Prescriber Uptake and Use of Novel Lipid‐Lowering Therapies — Evelyn Sarnes, Anand Gupta, et al. · Journal of the American Heart Association (2025) | TGRS Research Map | TGRS