Hemostatic effects of combined Thymus vulgaris and Medicago sativa extracts: in-silico and in-vivo study

Combined extracts of T. vulgaris and M. sativa significantly influence coagulation, especially the extrinsic pathway. The presence of aromatic, hydroxyl, alcoholic, and phenolic groups in these compounds likely contributes to their interaction with coagulation factors. These findings support the potential development of plant-based hemostatic agents for clinical use.