18F-FDG PET/CT Findings in Glandular Tularemia

A 47-year-old woman presented with fever, fatigue, night sweats and inguinal glandular swelling following a tick bite. Weeks of diagnostic uncertainty followed, and a lymph node biopsy was sent to be investigated for tularemia and pathology. An <sup>18</sup>F-FDG PET/CT scan was performed due to a suspicion of malignant lymphoma. The scan revealed high metabolic activity in the left inguinal region, which was compatible with abscesses. The diagnosis of glandular tularemia was established on a positive PCR for <i>Francisella tularensis</i> (<i>F. tularensis</i>) and positive <i>F. tularensis</i> serology. This case highlights the challenges of diagnosing tularemia and illustrates the role of imaging.

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Publication Details

Journal
Diagnostics
Published
2025-05-02
DOI
https://doi.org/10.3390/diagnostics15091159
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.00

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article

18F-FDG PET/CT Findings in Glandular Tularemia

Finn Gustafsson, Karl Keigo Rasmussen, Kristina Thorsteinsson, Anne‐Mette Lebech et al.
Diagnostics
Bacillus and Francisella bacterial research
article

18F-FDG PET/CT Findings in Glandular Tularemia

Finn Gustafsson, Karl Keigo Rasmussen, Kristina Thorsteinsson, Anne‐Mette Lebech, Lasse Fjordside
article en

Abstract

A 47-year-old woman presented with fever, fatigue, night sweats and inguinal glandular swelling following a tick bite. Weeks of diagnostic uncertainty followed, and a lymph node biopsy was sent to be investigated for tularemia and pathology. An <sup>18</sup>F-FDG PET/CT scan was performed due to a suspicion of malignant lymphoma. The scan revealed high metabolic activity in the left inguinal region, which was compatible with abscesses. The diagnosis of glandular tularemia was established on a positive PCR for <i>Francisella tularensis</i> (<i>F. tularensis</i>) and positive <i>F. tularensis</i> serology. This case highlights the challenges of diagnosing tularemia and illustrates the role of imaging.

DiagnosticsVol. 15(9)
University of Copenhagen (DK), Bispebjerg Hospital (DK), Copenhagen University Hospital (DK), Rigshospitalet (DK)
Gentofte Hospital, Lundbeckfonden, Rigshospitalet, H. Lundbeck A/S
Good health and well-being
Openalex Percentile: Top 92%
Bacillus and Francisella bacterial research
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18F-FDG PET/CT Findings in Glandular Tularemia — Finn Gustafsson, Karl Keigo Rasmussen, et al. · Diagnostics (2025) | TGRS Research Map | TGRS