Cytomegalovirus reactivation in the lower respiratory tract as an independent risk factor for mortality in critically Ill patients
Cytomegalovirus reactivation in the LRT is associated with poor outcomes in critically ill patients. Anti-cytomegalovirus therapy was not associated with overall survival outcomes; however, the subgroup with radiologic findings of cytomegalovirus pneumonia suggested benefits, while the subgroup with bacterial co-infections suggested harmful effects. Randomized controlled trials are needed.
Authors
- Yoon Hae Ahn (ORCID: https://orcid.org/0000-0002-3121-957X)
- Hyeon Jae Jo (ORCID: https://orcid.org/0000-0002-0017-3548)
- Hong Yeul Lee (ORCID: https://orcid.org/0000-0002-3638-8890)
- Chan Mi Lee (ORCID: https://orcid.org/0000-0001-7907-0412)
- Pyoeng Gyun Choe (ORCID: https://orcid.org/0000-0001-6794-7918)
- Nam Joong Kim (ORCID: https://orcid.org/0000-0001-6793-9467)
- Chang Kyung Kang (ORCID: https://orcid.org/0000-0003-1952-072X)
- Joong‐Yub Kim (ORCID: https://orcid.org/0000-0002-8272-3178)
- Sang‐Min Lee (ORCID: https://orcid.org/0000-0002-1388-9318)
- Jinwoo Lee (ORCID: https://orcid.org/0000-0003-0958-106X)
- Wan Beom Park (ORCID: https://orcid.org/0000-0003-0022-9625)
Institutions
- Harvard University (US)
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Critical Care
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s13054-025-05324-8
- Citations
- 3
- Primary Topic
- Cytomegalovirus and herpesvirus research
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea