Causal Associations Between Lipids, NPC1L1, and Liver Cancer Risk: Insights From Mendelian Randomization and Bioinformatics
The study demonstrates that elevated LDL-C levels are associated with a reduced risk of liver cancer and NPC1L1 plays a key role in regulating lipid metabolism and influencing immune evasion.
Authors
- Lili Wu (ORCID: https://orcid.org/0000-0002-1319-7274)
- Dianke Chen
- Yuankai Wu
- Xiaoyan Guo
- Jing Lai
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1111/jgh.16897
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94