Instantaneous in vivo distal edge verification in intensity‐modulated proton therapy by means of PET imaging
This study demonstrated the feasibility of instantaneous distal edge verification using PET imaging by introducing beam spot delays during dose delivery. The findings represent a first step toward the clinical implementation of instantaneous in vivo distal edge verification. The approach contributes to the development of real-time range verification aimed at improving IMPT treatments by mitigating range and setup uncertainties, thereby reducing dose to organs-at-risk and ultimately enhancing patient outcomes.
Authors
- Jeffrey Free (ORCID: https://orcid.org/0000-0002-1573-2613)
- Stefan Both (ORCID: https://orcid.org/0000-0001-6652-6054)
- P. Dendooven (ORCID: https://orcid.org/0000-0003-1859-1315)
- Zahra Ahmadi Ganjeh (ORCID: https://orcid.org/0000-0002-7331-1243)
- Brian Zapien‐Campos (ORCID: https://orcid.org/0000-0001-6093-6159)
- Giuliano Perotti‐Bernardini
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Medical Physics
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1002/mp.17850
- Citations
- 2
- Primary Topic
- Radiation Therapy and Dosimetry
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- KWF Kankerbestrijding
- Siemens Healthineers