The Role of Repeat Skeletal Muscle Biopsy: Indications, Yield and Outcomes
Repeat muscle biopsy achieved a specific diagnosis in 43% of cases and frequently impacted clinical decision-making. The highest yield was when IBM was suspected clinically, or when B1 showed non-specific myopathy. Non-specific myopathy may progress to histological atrophy; the role of untreated inflammation in driving this is unclear.
Authors
- Barbara Koszyca
- Thomas Khoo (ORCID: https://orcid.org/0000-0003-1122-3384)
- Bernice Gutschmidt
- Vidya Limaye (ORCID: https://orcid.org/0000-0002-8142-9532)
- Sarah Saxon
Institutions
- South Australia Pathology (AU)
- Royal Adelaide Hospital (AU)
- Women's and Children's Health Network (AU)
- The University of Adelaide (AU)
Publication Details
- Journal
- Muscle & Nerve
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1002/mus.28426
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hospital Research Foundation
- Australian Government
- University of Adelaide