Mendelian Randomization Identifies Putative Aging‐Related Causal Genes With Diagnostic Potential in Ulcerative Colitis
We identified three aging-related genes (IRF1, ME2, ERBB2) through SMR for the first time that are causally correlated to the risk of UC. Further analysis revealed their diagnostic potential and explored their correlation with immune infiltration in UC.
Authors
- Qi Liu (ORCID: https://orcid.org/0000-0002-7121-8563)
- Ying Jiang (ORCID: https://orcid.org/0000-0003-3378-1969)
- Qi Dong Zhao (ORCID: https://orcid.org/0000-0001-9713-1864)
- Di Zhang
- Xiangfei Sun (ORCID: https://orcid.org/0000-0001-6020-7925)
Institutions
- Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Annals of Human Genetics
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1111/ahg.12600
- Citations
- 1
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Natural Science Foundation of Shandong Province