Performance of cryptogenic new onset refractory status epilepticus score in a Brazilian cohort after testing for antineuronal antibodies with tissue‐based and cell‐based assays
In this cohort, AE was the most identified cause of NORSE, and 51% were cryptogenic. c-NORSE score ≥ 5 had a specificity of 100% (95% CI = 84%-100%) for identifying cryptogenic cases, whereas a score < 5 indicates additional investigation should be ordered. Although the sensitivity of the c-NORSE score was lower than previously reported, suggesting it may vary depending on complementary investigation, it is a useful tool for bedside NORSE evaluation in low-income countries, where access to antineuronal abs is limited.
Authors
- Aline Freire Borges Juliano
- Clécio Godeiro‐Júnior (ORCID: https://orcid.org/0000-0002-4312-1633)
- Dayane Danieli
- Luís Eduardo Coelho Andrade (ORCID: https://orcid.org/0000-0001-8742-9931)
- Fabio Fieni Toso (ORCID: https://orcid.org/0009-0008-4116-7858)
- Adaucto Wanderley da Nóbrega (ORCID: https://orcid.org/0009-0003-2727-2233)
- Verena Endmayr (ORCID: https://orcid.org/0000-0001-5279-5720)
- Alessandra Dellavance (ORCID: https://orcid.org/0000-0001-8789-3785)
- Omar Gurrola Arambula (ORCID: https://orcid.org/0000-0003-0042-2302)
- Fábio Siquineli (ORCID: https://orcid.org/0000-0002-5380-3654)
- Vanessa Daccach Marques (ORCID: https://orcid.org/0000-0002-2131-9438)
- Taissa Ferrari‐Marinho (ORCID: https://orcid.org/0000-0002-2971-3552)
- Lorena Pitombeira Sanders
- Eduardo Ferracioli Fusão
- Lívia Almeida Dutra (ORCID: https://orcid.org/0000-0001-6309-9077)
- Renata Barbosa Paolilo (ORCID: https://orcid.org/0000-0003-3548-8467)
- Karla Oliveira Couto
- Letícia Januzi de Almeida Rocha (ORCID: https://orcid.org/0000-0003-2738-9346)
- João Henrique Fregadolli Ferreira (ORCID: https://orcid.org/0000-0002-5226-8354)
- Fernanda Carvalho (ORCID: https://orcid.org/0000-0001-6548-7268)
- A. Gomes (ORCID: https://orcid.org/0000-0003-3069-0404)
- Paulo Ribeiro Nóbrega (ORCID: https://orcid.org/0000-0002-0021-9358)
- Ronaldo Maciel Dias (ORCID: https://orcid.org/0000-0003-3987-9596)
- Eduardo Sousa de Melo (ORCID: https://orcid.org/0000-0002-0952-6653)
- Tércio Luz Barbosa (ORCID: https://orcid.org/0000-0002-9285-7460)
- Mariana Braatz Krueger (ORCID: https://orcid.org/0000-0001-9485-7520)
- Renata Brasileiro Reis Pereira (ORCID: https://orcid.org/0009-0009-6796-4318)
- Adélia Maria de Miranda Henriques‐Souza (ORCID: https://orcid.org/0000-0002-5303-5528)
- Romana Höftberger (ORCID: https://orcid.org/0000-0002-5769-1100)
- Filipe Nolasco de Souza e Silva
- Kátia Lin (ORCID: https://orcid.org/0000-0002-5401-7524)
- Caio César Diniz Disserol (ORCID: https://orcid.org/0000-0001-7568-0897)
- Pedro Braga‐Neto
- Luís Otávio Sales Ferreira Caboclo (ORCID: https://orcid.org/0009-0001-4956-5542)
- Mara Lúcia Schmitz Ferreira Santos (ORCID: https://orcid.org/0000-0002-5253-988X)
- Sabrina Stephanie Lana Diniz (ORCID: https://orcid.org/0000-0001-6127-7941)
- Fernando Tenório Gameleira
- Georgia Lelis Aranha Tavares
- João Pedro Izidoro Gomes
- Emily Lima Marmentini
- Anderson de Cuffa
- Ana Carolina Zetehaku (ORCID: https://orcid.org/0000-0002-5668-7150)
- Katia Werneck Seitz
Institutions
- Universidade Federal de Minas Gerais (BR)
- Universidade Federal de Mato Grosso do Sul (BR)
- Universidade de Ribeirão Preto (BR)
- Universidade de São Paulo (BR)
- Universidade Federal do Ceará (BR)
- Universidade Federal de Pernambuco (BR)
- Hospital Israelita Albert Einstein (BR)
- Hospital de Base (BR)
- Universidade Estadual de Mato Grosso do Sul (BR)
- Universidade Federal do Piauí (BR)
- Universidade de Fortaleza (BR)
- Universidade Federal do Rio Grande do Norte (BR)
- Universidade Federal de Santa Catarina (BR)
- Hospital Universitário Walter Cantídio (BR)
- Hospital Erasto Gaertner (BR)
- Instituto de Medicina Integral Professor Fernando Figueira (BR)
- Hospital Santa Izabel (BR)
- Polydoro Ernani de São Thiago University Hospital (BR)
- Hospital Universitário da Universidade Federal do Maranhão (BR)
- Grupo Hospitalar Conceição (BR)
- Hospital de Clínicas Universidade Federal do Paraná (BR)
- Hospital Universitário de Brasília (BR)
- Hospital Infantil Joana de Gusmão (BR)
- Hospital Infantil Albert Sabin (BR)
- Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
- Fleury S.A. (Brazil) (BR)
- Instituto de Neurologia de Curitiba (BR)
- Hospital da Restauração (BR)
- Hospital Geral de Fortaleza (BR)
- Medical University of Vienna (AT)
- Universidade Federal de Alagoas (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1111/epi.18374
- Citations
- 2
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.78