Outcome of Bloodstream Infections Caused by Antibiotic-Resistant Bacteria: A 7-Year Retrospective Study at the University Hospital of Palermo, Italy
We observed an increasing trend in overall bacteremia-related mortality from 2018 to 2024. Microbiological data highlight the predominance of non-<i>aureus</i> staphylococci, <i>K. pneumoniae</i>, and <i>S. aureus</i> as leading pathogens of BSI, with <i>A. baumannii</i> emerging as a significant threat, particularly in ICUs. Rising antimicrobial resistance, especially among <i>K. pneumoniae</i>, underscores the urgent need for robust antimicrobial stewardship programs. <i>K. pneumoniae</i> and <i>A. baumannii</i> were associated with higher mortality.
Authors
- Raffaella Rubino
- Salvatore Antonino Distefano
- Alberto Firenze (ORCID: https://orcid.org/0000-0002-7383-3041)
- Luca Pipitò (ORCID: https://orcid.org/0000-0002-1871-4285)
- Anna Giammanco (ORCID: https://orcid.org/0000-0002-7874-6289)
- Eleonora Bono
- Antonio Cascio (ORCID: https://orcid.org/0000-0002-1992-1796)
- Chiara Vincenza Mazzola (ORCID: https://orcid.org/0009-0003-8975-4916)
- Celestino Bonura (ORCID: https://orcid.org/0000-0002-6250-9203)
- Antonio Anastasia
Institutions
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Antibiotics
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3390/antibiotics14050464
- Citations
- 6
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 7.91