Normative structural connectome constrains spreading transient brain activity in generalized epilepsy
Our findings suggest that the structural connectome shapes the spatial patterning of brain activity abnormalities, advancing our understanding of the network-level mechanisms underlying vulnerability to abnormal brain activity onset and propagation in GGE-GTCS.
Authors
- Zhiqiang Zhang (ORCID: https://orcid.org/0000-0002-3993-7330)
- Siqi Yang (ORCID: https://orcid.org/0009-0008-4751-1664)
- Jinpeng Niu (ORCID: https://orcid.org/0000-0002-6448-6615)
- Yao Meng (ORCID: https://orcid.org/0000-0003-2013-5183)
- Jie Xia (ORCID: https://orcid.org/0000-0003-3189-4425)
- Wei Liao (ORCID: https://orcid.org/0000-0001-7406-7193)
- Jiao Li (ORCID: https://orcid.org/0000-0002-2720-7111)
Institutions
- University of Electronic Science and Technology of China (CN)
- Chengdu University of Information Technology (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Chengdu University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1186/s12916-025-04099-7
- Citations
- 4
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.29
Funders
- National Natural Science Foundation of China
- University of Electronic Science and Technology of China
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities