MR-guided Laser Interstitial Thermal Therapy mesencephalotomy for medically intractable malignant pain
Stereotactic mesencephalotomy is a neurosurgical technique designed to sever spinothalamic pain transmission pathways for medically intractable pain. This report presents the first case of Magnetic Resonance-guided Laser Interstitial Thermal Therapy (MRgLITT) mesencephalotomy for severe malignant pain due to metastatic melanoma. The procedure significantly reduced the patient's pain, with a postoperative visual analog scale (VAS) score decreasing from > 7 to < 3. No adverse effects were observed. The case underscores the potential of MRgLITT mesencephalotomy as a precise, minimally invasive option for pain management in palliative care settings.
Authors
- Jean‐Philippe Arnault (ORCID: https://orcid.org/0000-0001-6156-473X)
- Mickael Aubignat (ORCID: https://orcid.org/0000-0001-5183-1128)
- Jean‐Marc Constans (ORCID: https://orcid.org/0000-0002-6751-4378)
- Martial Ouendo
- C. Desenclos
- Michel Lefranc
- Claire Josse
Institutions
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Groupe de REcherche en Cardio Oncologie (FR)
- Université de Picardie Jules Verne (FR)
Publication Details
- Journal
- Acta Neurochirurgica
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1007/s00701-025-06544-1
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 0.00