Surrogate Markers of Intestinal Permeability, Bacterial Translocation and Gut–Vascular Barrier Damage Across Stages of Cirrhosis
Surrogate markers of bacterial gut barrier dysfunction and bacterial translocation like ZFP, LBP and EndoCAb appear of limited use in advanced stages of cirrhosis and are confounded by hepatic synthesis capacity, portal congestion and acute phase responses. The prognostic implications of circulating PV-1 in decompensated cirrhosis levels demand further investigation.
Authors
- Karsten Große (ORCID: https://orcid.org/0000-0003-1013-6297)
- Johanna Reißing
- Tony Bruns (ORCID: https://orcid.org/0000-0002-5576-6914)
- Philipp A. Reuken (ORCID: https://orcid.org/0000-0002-7696-475X)
- Mick Frissen
- Andreas Stallmach (ORCID: https://orcid.org/0000-0002-6101-5244)
- René Aschenbach (ORCID: https://orcid.org/0000-0003-3775-0449)
- Ulf Teichgräber (ORCID: https://orcid.org/0000-0002-4048-3938)
- Majda El‐Hassani
- Frederic Haedge
Institutions
- Jena University Hospital (DE)
- Friedrich Schiller University Jena (DE)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Liver International
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1111/liv.70119
- Citations
- 9
- Primary Topic
- Liver Disease and Transplantation
- Type
- article
- Field-Weighted Citation Impact
- 11.90
Funders
- Deutsche Forschungsgemeinschaft