A new approach to haemoglobin oxygen affinity research at high altitude: Determination of haemoglobin oxygen dissociation curves and 2,3-bisphosphoglycerate in an experimental human crossover hypoxic chamber study
The 2,3-BPG increase after 96 h in HH compensates the effect of hypoxia-induced decrease in P<sub>et</sub>CO<sub>2</sub>/increase in pH on the ODC.
Authors
- Christoph Siebenmann (ORCID: https://orcid.org/0000-0002-0315-3761)
- Hermann Brugger (ORCID: https://orcid.org/0000-0003-2752-6929)
- Giacomo Strapazzon (ORCID: https://orcid.org/0000-0002-4402-8633)
- Maja Schlittler (ORCID: https://orcid.org/0000-0002-3886-9612)
- Ivo B. Regli (ORCID: https://orcid.org/0000-0002-0697-803X)
- Simon Woyke (ORCID: https://orcid.org/0000-0002-1241-1734)
- Mathias Ströhle (ORCID: https://orcid.org/0000-0002-6623-7823)
- David Plunser
- Hannes Gatterer (ORCID: https://orcid.org/0000-0002-5084-2930)
- Herbert Oberacher (ORCID: https://orcid.org/0000-0002-0963-8268)
- Thomas Haller (ORCID: https://orcid.org/0000-0001-9147-4081)
- Rachel Turner (ORCID: https://orcid.org/0000-0003-4371-580X)
Institutions
- Eurac Research (IT)
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Institute of Mountain Emergency Medicine (IT)
Publication Details
- Journal
- European Journal of Applied Physiology
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1007/s00421-025-05806-1
- Citations
- 2
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 3.63
Funders
- Swiss National Centre of Competence in Research Kidney Control of Homeostasis