OBSTETRICS AND FETAL OUTCOME OF PREGNANT WOMEN WHO IS ST ND INFECTED IN 1 AND 2 TRIMESTER OF PREGNANCY- PROSPECTIVE OBSERVATIONAL STUDY

BACKGROUND: In December 2019 a novel strain of coronavirus, was rst isolated by the Chinese Centre for Disease Control and Prevention. This strain connected to the cluster of acute respiratory illness cases from Wuhan, China was later ofcially named as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2). On 30th January 2020, WHO declared the outbreak of SARS-Cov-2 a public health emergency of international concern, and on 11th March 2020 declared it to be a pandemic. Pregnant women are known to be at higher risk of severe morbidity and mortality from respiratory infections such as inuenza and SARS, making a strong case for pregnant women to be considered an at-risk population for COVID-19. The risks of adverse maternal and perinatal outcomes are not very clear in coronavirus disease 2019 (COVID-19)-positive pregnant women (who is infected in 1st and 2nd trimester of pregnancy). Therefore, this study aimed to determine the maternal and fetal outcome in COVID 19 positive pregnancies.(infected in <26 weeks of pregnancies) METHODS: This is Prospective observational study of 50 cases based on compiled clinical data for pregnant women with COVID 19 infection between April 2020 – September 2020(6 months) . a laboratory conrmed positive cases of COVID 19 infection in pregnant women were included. we included all pregnant women coming to new civil hospital Surat who had COVID-19 in1st and 2nd trimester pregnancies and then follow up of obstetrics and fetal outcome taken via telephonic contact. RESULTS: In our study, majority of subjects had full term vaginal delivery ( 38%)and followed by 22% subjects had full term LSCS . total 26% were abortions. In neonatal outcome ,Majority had live birth which was 66% , majority had birthweight between 2.6 – 3.5 kg. 18% babies had NICU admission out of which 8% due to prematurity.14% babies discharged successfully. CONCLUSION: In our study most of subjects who had covid 19 infection in 1st and 2nd trimester of pregnancy had full term vaginal delivery. Majority of babies were covid negative and had birth weight within normal range.COVID-19 pandemic affects the pregnant women along with the general population. As the pandemic waves continues to recur with newer strains, the obstetricians have to be vigilant. The pregnant women with severe disease have to be given intensive multidisciplinary care to prevent maternal and fetal morbidity and mortality