Bone Marrow Infection by Pneumocystis jirovecii in a Patient with AIDS: A Case Report and Literature Review
This case highlights a rare presentation of disseminated <i>Pneumocystis jirovecii</i> infection with bone marrow involvement in a patient with advanced HIV/AIDS. Although infrequent, this complication should be considered in individuals with <i>Pneumocystis jirovecii</i> pneumonia who develop persistent cytopenias and systemic symptoms. Diagnosis depends on histopathologic confirmation, which may lead to under-recognition. Early suspicion and individualized management are essential, though the optimal treatment approach for extrapulmonary infection remains undefined.
Authors
- Diego Alejandro Cubides-Díaz (ORCID: https://orcid.org/0000-0003-3935-4394)
- Carlos Álvarez (ORCID: https://orcid.org/0000-0001-5419-4494)
- Carlos Mauricio Calderón-Vargas (ORCID: https://orcid.org/0000-0003-1408-3954)
- Valentina Negrette-Lazaro (ORCID: https://orcid.org/0009-0002-2979-1312)
- Viviana Poveda-Hurtado
- Juan Pablo López-Salazar
Institutions
- Universidad de La Sabana (CO)
- Universidad Nacional de Colombia (CO)
- Hospital Universitario de la Samaritana (CO)
- Fundación Universitaria Sanitas (CO)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Infectious Disease Reports
- Published
- 2025-05-02
- DOI
- https://doi.org/10.3390/idr17030047
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00