Retinoic Acid Receptor Alpha- and Beta-Mediated Signaling Regulates Conjunctival Epithelial Cell Keratinization
Keratinization of CjECs involves RARA or RARB-mediated pathways, and ATRA and Am80 alter the expression of vitamin A pathway gene and suppress keratinization.
Authors
- Mayumi Ueta (ORCID: https://orcid.org/0000-0002-2678-5024)
- Shigeru Kinoshita (ORCID: https://orcid.org/0000-0002-6839-251X)
- Hokoru Yoshioka
- Katsura Mizushima (ORCID: https://orcid.org/0000-0001-5481-7022)
- Norihiko Yokoi (ORCID: https://orcid.org/0000-0003-4839-3416)
- Chie Sotozono
- Yuji Naito
- Seiichi Yokoo
Institutions
- Kyoto Prefectural University of Medicine (JP)
- University of Tokyo Hospital (JP)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1167/iovs.66.5.6
- Primary Topic
- Ocular Surface and Contact Lens
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Japan Agency for Medical Research and Development
- Ministry of Education, Culture, Sports, Science and Technology