Enantiomeric separation of drugs by HPLC

The need to separate drug enantiomers isn't just a technical challenge it s a crucial aspect of making medicines safer and more effective. High-Performance Liquid Chromatography (HPLC) has proven itself as a reliable tool for achieving precise and reproducible enantiomeric separations. This review explores various strategies for enantiomeric separation via HPLC, from the use of chiral stationary phases to clever tweaks in the mobile phase. We ll also dive into real-world applications, the hurdles researchers face, and how the field is evolving.