Qingshu Yiqi decoction ameliorates exertional heat stroke-induced intestinal barrier injury via NF-κB/MLC pathway and gut microbiota
QSYQD protects against EHS-induced damage by preserving intestinal barrier integrity, modulating gut microbiota, and inhibiting the NF-κB and MLC signaling pathways. Future studies will focus on identifying active compounds within QSYQD that enhance heat tolerance and provide EHS protection.
Authors
- Hanyu Zhu (ORCID: https://orcid.org/0000-0002-8729-4245)
- Yanhua Gong (ORCID: https://orcid.org/0000-0002-2693-0498)
- Jianyao You
- Yangyang Cao (ORCID: https://orcid.org/0000-0001-7935-6170)
- Wenjun Chang (ORCID: https://orcid.org/0000-0002-8476-4731)
- Shuogui Xu (ORCID: https://orcid.org/0000-0001-5926-4391)
- Ji‐Kuai Chen
- Jun Ma (ORCID: https://orcid.org/0000-0002-1137-9349)
- Yawei Wang (ORCID: https://orcid.org/0000-0002-8754-0485)
- Lei Li (ORCID: https://orcid.org/0000-0002-4942-1100)
- Qing Song (ORCID: https://orcid.org/0009-0002-8676-9525)
- Jiawei Zhou (ORCID: https://orcid.org/0000-0002-1844-9178)
- Weiyi Ma
- Juelin Chen
- Yankun Pei
- Man Wang (ORCID: https://orcid.org/0000-0001-7190-4582)
Institutions
- Second Military Medical University (CN)
- Chinese PLA General Hospital (CN)
- Changhai Hospital (CN)
- Hainan 301 Hospital (CN)
Publication Details
- Journal
- Phytomedicine
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1016/j.phymed.2025.156723
- Citations
- 9
- Primary Topic
- Thermoregulation and physiological responses
- Type
- article
- Field-Weighted Citation Impact
- 10.48