Bilateral Focused Ultrasound Thalamotomy for Essential Tremor: Clinical Outcomes Compared to Bilateral <scp>Deep Brain Stimulation</scp> and Probabilistic Lesion Mapping
The efficacies of bilateral MRgFUS and DBS appear comparable. MRgFUS probabilistic maps vary with different targeting methods, revealing two distinct sweet spots: dorsal Vim-Vop border and ventral Vim/PSA. © 2025 The Author(s). Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Authors
- Clemens Neudorfer (ORCID: https://orcid.org/0000-0002-3153-1045)
- Brendan Santyr (ORCID: https://orcid.org/0000-0003-1782-4527)
- Benjamin Davidson (ORCID: https://orcid.org/0000-0001-5264-1190)
- Jürgen Germann (ORCID: https://orcid.org/0000-0003-0995-8226)
- Talyta Grippe (ORCID: https://orcid.org/0000-0003-3126-8002)
- Kazuaki Yamamoto (ORCID: https://orcid.org/0000-0001-7362-6707)
- Cletus Cheyuo (ORCID: https://orcid.org/0000-0002-9717-3738)
- Alexandre Boutet (ORCID: https://orcid.org/0000-0001-6942-5195)
- Suneil K. Kalia (ORCID: https://orcid.org/0000-0003-2054-1915)
- Ajmal Zemmar (ORCID: https://orcid.org/0000-0003-1463-3338)
- Christian Iorio‐Morin (ORCID: https://orcid.org/0000-0003-2995-7255)
- Oliver Flouty (ORCID: https://orcid.org/0000-0001-5990-7297)
- Franziska Schmidt
- Andrew Yang (ORCID: https://orcid.org/0000-0002-7023-9880)
- Alfonso A. Fasano (ORCID: https://orcid.org/0000-0001-5346-0180)
- Renato P. Munhoz (ORCID: https://orcid.org/0000-0002-4783-4067)
- Artur Vetkas (ORCID: https://orcid.org/0000-0002-4487-432X)
- Andrés M. Lozano (ORCID: https://orcid.org/0000-0001-8257-3694)
- Nardin Samuel (ORCID: https://orcid.org/0000-0002-5007-4134)
- Mojgan Hodaie (ORCID: https://orcid.org/0000-0001-6278-4929)
- Michael Colditz (ORCID: https://orcid.org/0000-0002-7908-2146)
- Can Sarica (ORCID: https://orcid.org/0000-0001-8419-7426)
- Ghazaleh Darmani (ORCID: https://orcid.org/0000-0002-4073-1911)
- Anton Fomenko (ORCID: https://orcid.org/0000-0003-4131-6784)
- Robert Chen (ORCID: https://orcid.org/0000-0002-8371-8629)
Institutions
- University Health Network (CA)
- Université de Sherbrooke (CA)
- Harvard University (US)
- University of Louisville (US)
- The University of Queensland (AU)
- University of Toronto (CA)
- University of South Florida (US)
- Toronto Western Hospital (CA)
- Tartu University Hospital (EE)
- Massachusetts General Hospital (US)
- Lahey Medical Center (US)
- Neurological Surgery (US)
- Krembil Research Institute
Publication Details
- Journal
- Movement Disorders
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1002/mds.30221
- Citations
- 7
- Primary Topic
- Neurological disorders and treatments
- Type
- article
- Field-Weighted Citation Impact
- 9.72
Funders
- Michael J. Fox Foundation for Parkinson's Research
- Focused Ultrasound Foundation
- Boston Scientific Corporation
- Sunovion
- Multiple System Atrophy Coalition
- University of Toronto
- Novo Nordisk
- Parkinson Canada
- Ipsen
- Canadian Institutes of Health Research