Risk of fragility fracture is aggravated during bone regeneration processes in osteoporotic sheep
Osteoporosis causes uneven degradation to trabecular tissue quality across different bone locations. Furthermore, the bone regeneration process via bone transport in osteoporotic subjects leads to a systemic skeletal disorder that further impairs the bone quality, surpassing the damage caused by osteoporosis alone. This impairment appears to be intensified by the pre-existing osteoporotic condition.
Authors
- Rocío Navarrete (ORCID: https://orcid.org/0000-0003-4605-4162)
- Jaime Domínguez (ORCID: https://orcid.org/0000-0002-0491-7911)
- Esther Reina-Romo (ORCID: https://orcid.org/0000-0002-5714-465X)
- Juan Mora‐Macías (ORCID: https://orcid.org/0000-0002-7997-9789)
- Juán Morgaz
- Pablo Blázquez-Carmona (ORCID: https://orcid.org/0000-0002-7605-5812)
- Juan J. Toscano-Angulo (ORCID: https://orcid.org/0000-0001-7946-2408)
Institutions
- Universidad de Cádiz (ES)
- University of Córdoba (ES)
- Universidad de Huelva (ES)
- Universidad de Sevilla (ES)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1371/journal.pone.0319910
- Citations
- 1
- Primary Topic
- Bone health and osteoporosis research
- Type
- article
- Field-Weighted Citation Impact
- 1.72