Sustainable Green Synthesis, Characterization and Anti-Microbial Testing of Cu-Based Metal-Organic Framework (MOF)/TiO2 Nanocomposites Derived from Cinnamomum Verum Bark

This research work is aimed at green synthesis with sustainability towards the production of copper (Cu)-Based Metal Organic Framework (MOF) and their doping in titanium dioxide (TiO₂) nanoparticles synthesized using a natural reductant and stabilizer, Cinnamomum verum (C. verum) bark extract. It is an eco-friendly synthesis technique because the bioactive compounds such as flavonoids and polyphenols present in C. verum help reduce and stabilize metal ions, thus replacing toxic chemicals. The synthesized Cu-doped TiO₂ nanocomposites are found to absorb increased visible light owing to the reduced bandgap from copper doping, as observed by UV-Vis Diffuse Reflectance Spectroscopy (UV-DRS). The scanning electron microscopy and energy-dispersive X-ray spectroscopy analysis of the synthesized nanocomposites indicates that the distribution of Cu in the TiO₂ matrix is uniform, which offers structural stability and functional efficacy. Well-diffusion experiments on antimicrobial studies reveal that the nanocomposites produced by this process have excellent antimicrobial activity, especially towards Staphylococcus aureus. This is attributed to the photoinduced generation of ROS, which can break cell walls and interfere with microbial cell metabolism. The synthesis process for this Cu-TiO2 nanocomposite is totally in compliance with green chemistry principles and produces nanocomposites having strong antimicrobial and photocatalytic action. These results outline the grand potential of green methods-prepared Cu-doped TiO₂ nanocomposites to be used in antimicrobial coatings, environmental remediation, and much more - opening a promising route towards sustainable nanotechnology development.