Evaluation of the responsiveness of the Keratosis Pilaris Investigator Global Assessment Score (KP-IGA) and composite KP Area Index (KPAI)
This study aimed to evaluate the responsiveness and determine minimal clinically important differences (MCIDs) of the Keratosis Pilaris Investigator Global Assessment (KP-IGA) and the composite KP Area Index (KPAI) in 16 patients undergoing laser treatment. KPAI demonstrated greater responsiveness than KP-IGA, with MCIDs of 1 and 5, respectively, and severity cut-offs of 10 for moderate and 34 for mild disease. These findings validate KP-IGA and KPAI as reliable scoring tools for KP clinical trials.
Authors
- Dedee Frances Murrell (ORCID: https://orcid.org/0000-0003-2971-0199)
- Boaz Shulruf (ORCID: https://orcid.org/0000-0003-3644-727X)
- Tangqi J Ng (ORCID: https://orcid.org/0009-0004-6720-0848)
- Madeline A Wang (ORCID: https://orcid.org/0000-0003-3876-5968)
- Pooi C Wong (ORCID: https://orcid.org/0000-0002-1300-6343)
- Anna Wilson (ORCID: https://orcid.org/0000-0001-5596-2109)
- Hossein Akbarialiabad (ORCID: https://orcid.org/0000-0003-2018-6378)
Institutions
- UNSW Sydney (AU)
- St George Hospital (AU)
Publication Details
- Journal
- British Journal of Dermatology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1093/bjd/ljaf163
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of New South Wales