Coronal Clival Cleft in CHARGE Syndrome: Fetal MRI Series
The most common fetal neuroimaging findings supporting the diagnosis of CHARGE syndrome are olfactory deficiency and inner ear dysplasia. Coronal clival clefts are often present and are frequently visible on prenatal MR imaging. The presence of a clival coronal cleft should raise the possibility of CHARGE syndrome, particularly when associated with other known cardinal findings, such as cerebellar dysgenesis, olfactory apparatus deficiency, and inner ear dysplasia.
Authors
- Nahla Khalek (ORCID: https://orcid.org/0000-0002-1510-7850)
- Matthew T. Whitehead (ORCID: https://orcid.org/0000-0001-5077-693X)
- Carmen Cerron-Vela (ORCID: https://orcid.org/0000-0002-7881-6021)
- Sara Reis Teixeira (ORCID: https://orcid.org/0000-0001-5845-058X)
- Renee Wright
Institutions
- Children's Hospital of Philadelphia (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3174/ajnr.a8609
- Citations
- 1
- Primary Topic
- Congenital Ear and Nasal Anomalies
- Type
- article
- Field-Weighted Citation Impact
- 0.00