[18F]flutemetamol uptake in the colon of a memory clinic population and its association with brain amyloidosis and the gut microbiota profile: an exploratory study
This exploratory study showed that subjects with cerebral amyloidosis have greater colonic FMM uptake than subjects with normal cerebral amyloid load, correlating with altered GM composition. Further analysis is needed to determine if these changes denote amyloid-related changes or other phenomena.
Authors
- Elena Gatti (ORCID: https://orcid.org/0000-0002-5529-9850)
- Marco Salvatore (ORCID: https://orcid.org/0000-0001-6402-2610)
- Rahel Park (ORCID: https://orcid.org/0000-0002-8751-2812)
- Giulia Quattrini (ORCID: https://orcid.org/0000-0002-3750-710X)
- Michela Pievani (ORCID: https://orcid.org/0000-0002-1794-8987)
- Max Scheffler
- Valentina Garibotto (ORCID: https://orcid.org/0000-0003-2422-698X)
- Marco Aiello (ORCID: https://orcid.org/0000-0002-3676-0664)
- Aurélien Lathuilière (ORCID: https://orcid.org/0000-0002-5191-5214)
- Débora Elisa Peretti (ORCID: https://orcid.org/0000-0002-3033-8817)
- Annamaria Cattaneo (ORCID: https://orcid.org/0000-0002-9963-848X)
- Moira Marizzoni (ORCID: https://orcid.org/0000-0003-3749-2988)
- Claire Chevalier (ORCID: https://orcid.org/0000-0003-0902-0756)
- Giovanni B. Frisoni (ORCID: https://orcid.org/0000-0001-7075-7082)
Institutions
- University of Geneva (CH)
- University of Milan (IT)
- University Hospital of Geneva (CH)
- Centro San Giovanni di Dio Fatebenefratelli (IT)
- Centre d'Imagerie BioMedicale (CH)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-05-02
- DOI
- https://doi.org/10.1007/s00259-025-07299-8
- Citations
- 2
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Ministero della Salute