Curcumin-loaded WPI-FUC emulsion as a microcapsule core material enhances the applicability and stability of curcumin—preparation and characterization of a new type of microcapsule

Emulsions stabilized by protein-polysaccharide complexes are effective carriers for delivering hydrophobic active substances, such as curcumin. Traditional microcapsules prepared using emulsions to load curcumin often exhibit unfavorable storage stability and applicability due to the susceptibility of the oils in the emulsion to oxidation. To address these two issues, this study first examined the stability and curcumin encapsulation efficiency of Emulsion I: a whey protein isolate (WPI) single-layer emulsion, Emulsion II: a WPI-fucoidan (FUC) single-layer emulsion, and Emulsion III: a WPI-FUC double-layer emulsion. Among them, due to the good spatial effect and electrostatic interaction of the WPI-FUC complex, which can inhibit the aggregation of droplets, the curcumin-loaded emulsion II has the best stability. Subsequently, we used curcumin-loaded Emulsion II as the core material, and maltodextrin (MD), inulin (IN), and maltodextrin-inulin complex (MD-IN), which are almost lipid-free and less prone to oxidation, individually as the wall materials, to prepare microcapsules through spray drying and freeze-drying processes. Microcapsules prepared with MD-IN as the wall material by spray drying have the optimal solubility, storage stability, and encapsulation efficiency. This novel microcapsule structure provides a certain data basis for the better application of the active substance in the food industry. • The influence of emulsion structure on emulsion stability. • The stability of WPI-FUC emulsion is superior to that of WPI emulsion. • Microcapsules are prepared using curcumin-loaded emulsions as the core material.

Authors

Institutions

Publication Details

Journal
LWT
Published
2025-05-01
DOI
https://doi.org/10.1016/j.lwt.2025.117854
Citations
4
Primary Topic
Microencapsulation and Drying Processes
Type
article
Field-Weighted Citation Impact
4.65
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Curcumin-loaded WPI-FUC emulsion as a microcapsule core material enhances the applicability and stability of curcumin—preparation and characterization of a new type of microcapsule

Liming Zheng, Yong Qin, Xing Chen, Ping Zhao et al.
4 citations
LWT
Microencapsulation and Drying Processes
4.65
article

Curcumin-loaded WPI-FUC emulsion as a microcapsule core material enhances the applicability and stability of curcumin—preparation and characterization of a new type of microcapsule

Liming Zheng, Yong Qin, Xing Chen, Ping Zhao, Wenyu Zhang, Qiushuo Chang, Liyuan Zheng, Chunyu Xi, Xuan Ding
article en
4 citations

Abstract

Emulsions stabilized by protein-polysaccharide complexes are effective carriers for delivering hydrophobic active substances, such as curcumin. Traditional microcapsules prepared using emulsions to load curcumin often exhibit unfavorable storage stability and applicability due to the susceptibility of the oils in the emulsion to oxidation. To address these two issues, this study first examined the stability and curcumin encapsulation efficiency of Emulsion I: a whey protein isolate (WPI) single-layer emulsion, Emulsion II: a WPI-fucoidan (FUC) single-layer emulsion, and Emulsion III: a WPI-FUC double-layer emulsion. Among them, due to the good spatial effect and electrostatic interaction of the WPI-FUC complex, which can inhibit the aggregation of droplets, the curcumin-loaded emulsion II has the best stability. Subsequently, we used curcumin-loaded Emulsion II as the core material, and maltodextrin (MD), inulin (IN), and maltodextrin-inulin complex (MD-IN), which are almost lipid-free and less prone to oxidation, individually as the wall materials, to prepare microcapsules through spray drying and freeze-drying processes. Microcapsules prepared with MD-IN as the wall material by spray drying have the optimal solubility, storage stability, and encapsulation efficiency. This novel microcapsule structure provides a certain data basis for the better application of the active substance in the food industry. • The influence of emulsion structure on emulsion stability. • The stability of WPI-FUC emulsion is superior to that of WPI emulsion. • Microcapsules are prepared using curcumin-loaded emulsions as the core material.

LWTVol. 224
Union Hospital (HK), Jilin University (CN), Union Hospital (CN), China Medical University (CN)
Openalex Percentile: Top 6%
Microencapsulation and Drying Processes
4.65
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.