Diagnosis of a congenital nodule labelled pigmented epithelioid melanocytoma unconfirmed by recent molecular biology tools

A newborn presented with an asymptomatic occipital bluish-black nodule measuring 20 ×10mm, with two ipsilateral pathological occipital lymph nodes. The nodule slowly increased in size, as shown in Fig. 1(a). The girl was born prematurely at 34 weeks of amenorrhea due to preeclampsia, without family history of cancer. Echography at 4 months revealed a mass with microcalcifications and peripheral hypervascularization, while MRI showed a bilobed intradermal mass. Radiographs of skull and chest were normal.

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Publication Details

Journal
EJC Paediatric Oncology
Published
2025-05-02
DOI
https://doi.org/10.1016/j.ejcped.2025.100234
Primary Topic
Cutaneous Melanoma Detection and Management
Type
article
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article

Diagnosis of a congenital nodule labelled pigmented epithelioid melanocytoma unconfirmed by recent molecular biology tools

Nicolas Macagno, N. Dégardin, Caroline Donzé, Arnauld Verschuur et al.
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EJC Paediatric Oncology
Cutaneous Melanoma Detection and Management
article

Diagnosis of a congenital nodule labelled pigmented epithelioid melanocytoma unconfirmed by recent molecular biology tools

Nicolas Macagno, N. Dégardin, Caroline Donzé, Arnauld Verschuur, Nicolás Ortonne
article en

Abstract

A newborn presented with an asymptomatic occipital bluish-black nodule measuring 20 ×10mm, with two ipsilateral pathological occipital lymph nodes. The nodule slowly increased in size, as shown in Fig. 1(a). The girl was born prematurely at 34 weeks of amenorrhea due to preeclampsia, without family history of cancer. Echography at 4 months revealed a mass with microcalcifications and peripheral hypervascularization, while MRI showed a bilobed intradermal mass. Radiographs of skull and chest were normal.

EJC Paediatric OncologyVol. 5
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Openalex Percentile: Top 86%
Cutaneous Melanoma Detection and Management
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