Efficacy of regular prophylaxis with a plasma-derived von Willebrand factor/factor VIII concentrate with a 1:1 activity ratio in reducing heavy menstrual bleeding in girls/women with von Willebrand disease
In these exploratory analyses, wilate prophylaxis given 2-3 times a week without menstruation coordination was efficacious in reducing heavy menstrual bleeding in girls/women with VWD compared with on-demand treatment. Long-term prophylaxis has the potential to play a major role in improving the care and reducing the disease burden for girls/women with VWD.
Authors
- Ana Boban (ORCID: https://orcid.org/0000-0003-3532-2336)
- Claudia Djambas Khayat (ORCID: https://orcid.org/0000-0002-5584-5049)
- Leonid Dubey (ORCID: https://orcid.org/0000-0003-1094-6708)
- Csongor Kiss (ORCID: https://orcid.org/0000-0001-5170-5965)
- Robert F. Sidonio (ORCID: https://orcid.org/0000-0002-9509-9415)
- Z Boda
Institutions
- University of Debrecen (HU)
- University Hospital Centre Zagreb (HR)
- Emory University (US)
- Saint Joseph University (LB)
- Lviv City Children's Hospital (UA)
Publication Details
- Journal
- AJOG Global Reports
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.xagr.2025.100501
- Citations
- 2
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.54