Five-year outcomes after surgical treatment of infant postinfectious hydrocephalus in sub-Saharan Africa: results of a randomized trial
These results suggest that ETV/CPC and VPS treatment have comparable long-term outcomes for infants in medically resource-constrained environments. Furthermore, brain volume strongly correlates with developmental and quality of life metrics, emphasizing the need to focus on optimizing brain volume growth potential in infants with severe perinatal neurological insults such as infection and hydrocephalus.
Authors
- Vishal Monga (ORCID: https://orcid.org/0000-0002-5100-2263)
- Steven J. Schiff (ORCID: https://orcid.org/0000-0003-2623-3614)
- John Mugamba
- Venkateswararao Cherukuri (ORCID: https://orcid.org/0000-0001-7854-2027)
- Joshua Magombe (ORCID: https://orcid.org/0000-0002-5017-0206)
- Abhaya V. Kulkarni (ORCID: https://orcid.org/0000-0002-1706-7004)
- Edith Mbabazi-Kabachelor (ORCID: https://orcid.org/0000-0001-7912-7116)
- Peter Ssenyonga
- Esther Nalule
- Mallory Peterson (ORCID: https://orcid.org/0000-0001-5734-9260)
- Justin Onen
- Benjamin C. Warf (ORCID: https://orcid.org/0000-0001-6376-4751)
Institutions
- Boston Children's Hospital (US)
- Pennsylvania State University (US)
- Harvard University (US)
- University of Toronto (CA)
- Mulago Hospital (UG)
- Hospital for Sick Children (CA)
- Yale University (US)
- CURE Children’s Hospital of Uganda (UG)
- Penn State Milton S. Hershey Medical Center (US)
Publication Details
- Journal
- Journal of Neurosurgery Pediatrics
- Published
- 2025-05-02
- DOI
- https://doi.org/10.3171/2025.1.peds24417
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91