Genetic predisposition to adiposity, and type 2 diabetes: the role of lifestyle and phenotypic adiposity
Whilst phenotypic adiposity explains a large proportion of the association between BMI-PRS/WHR-PRS and T2D, modifiable lifestyle factors also make contributions. Promoting healthy lifestyles among people prone to adiposity is important in reducing the global burden of T2D.
Authors
- Joey Ward (ORCID: https://orcid.org/0000-0003-0951-8511)
- Mengrong Zhang
- Jana Anderson (ORCID: https://orcid.org/0000-0001-7290-6635)
- Jill P. Pell (ORCID: https://orcid.org/0000-0002-8898-7035)
- Donald M. Lyall (ORCID: https://orcid.org/0000-0003-3850-1487)
- Carlos Celis‐Morales (ORCID: https://orcid.org/0000-0003-2612-3917)
- Rona J. Strawbridge (ORCID: https://orcid.org/0000-0001-8506-3585)
- Frederick K. Ho (ORCID: https://orcid.org/0000-0001-7190-9025)
Institutions
- Catholic University of the Maule (CL)
- Karolinska Institutet (SE)
- Karolinska Development (Sweden) (SE)
- University of Glasgow (GB)
- Arturo Prat University (CL)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2025-04-23
- DOI
- https://doi.org/10.1093/ejendo/lvaf084
- Citations
- 6
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 10.90
Funders
- Wellcome Trust
- British Heart Foundation
- Northwest Regional Development Agency
- China Scholarship Council
- Medical Research Council