Obinutuzumab is effective for the treatment of rituximab-refractory PLA2R-associated membranous nephropathy

Obinutuzumab mainly induces short-term partial remissions in patients with rituximab-refractory primary membranous nephropathy, which may be related to the short follow-up period. However, this study demonstrates that obinutuzumab is an effective and safe treatment for rituximab-refractory PLA2R-associated membranous nephropathy.

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Publication Details

Journal
Clinical Kidney Journal
Published
2025-05-01
DOI
https://doi.org/10.1093/ckj/sfaf026
Citations
8
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
11.45

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article

Obinutuzumab is effective for the treatment of rituximab-refractory PLA2R-associated membranous nephropathy

Wenyan Su, Jing-Sheng Men, Dan Liu, Jianyi Li et al.
8 citations
Clinical Kidney Journal
Renal Diseases and Glomerulopathies
11.45
article

Obinutuzumab is effective for the treatment of rituximab-refractory PLA2R-associated membranous nephropathy

Wenyan Su, Jing-Sheng Men, Dan Liu, Jianyi Li, Yunzhao Wang, Shuo Zhong, Rong Wang, Yao Zhang, Jing Sun, Haiping Wang, Jie Gao, Liang Xu
article en
8 citations

Abstract

Obinutuzumab mainly induces short-term partial remissions in patients with rituximab-refractory primary membranous nephropathy, which may be related to the short follow-up period. However, this study demonstrates that obinutuzumab is an effective and safe treatment for rituximab-refractory PLA2R-associated membranous nephropathy.

Clinical Kidney JournalVol. 18(5)
Shandong University (CN), Southeast University (BD), Shandong Provincial Hospital (CN), Jining First People's Hospital (CN), Shandong Provincial QianFoShan Hospital (CN), Shandong First Medical University (CN), Southeast University (CN), Nanjing Medical University (CN)
Natural Science Foundation of Shandong Province, Shandong First Medical University
Zero hunger
Openalex Percentile: Top 1%
Renal Diseases and Glomerulopathies
11.45
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