To Study the Effect of Chemical Peeling in Various Dermatological Conditions

Introduction: Chemical peeling is a widely utilized dermatological procedure for conditions such as acne, hyperpigmentation, melasma, and photoaging.It involves the controlled application of chemical agents to induce epidermal exfoliation and dermal regeneration, improving skin texture and pigmentation.Despite its effectiveness, variations in response and the potential for adverse effects necessitate further clinical evaluation.This study aims to assess the efficacy and safety of chemical peeling in various dermatological conditions.Methodology: A prospective, interventional study was conducted at department of dermatology in Rama Medical College Hospital and Research Centre over two years.A total of 100 patients with acne, melasma, post-inflammatory hyperpigmentation, and photoaging were included.Patients underwent standardized chemical peeling procedures using salicylic acid, glycolic acid, Jessner's solution, or trichloroacetic acid (TCA).Clinical assessments were performed at baseline, week 4, and week 8.Primary outcomes included reduction in acne lesions and melanin index, while secondary outcomes included patient satisfaction and adverse effects.Statistical significance was set at p < 0.05.Results: A significant reduction in acne lesions (71.7% at week 8, p < 0.001) and melanin index (56.3%reduction, p < 0.001) was observed.Patient satisfaction was high, with 78% rating the procedure as satisfactory or very satisfactory.Adverse effects were mild, with erythema (20%) and post-inflammatory hyperpigmentation (8%) being the most common.Conclusion: Chemical peeling is an effective and safe intervention for acne, hyperpigmentation, and photoaging, with high patient satisfaction and minimal adverse effects.Future studies should explore long-term efficacy and combination treatments to optimize patient outcomes.