Corticosteroid Use and Long-Term Changes in Weight and Waist Circumference: The Lifelines Cohort Study
This study demonstrates that CS use, including locally administered forms, is associated with long-term increases in weight and WC, notably in female individuals and those with overweight or obesity. Discontinuing CS was linked to reductions in WC. These findings underscore the need to carefully assess chronic systemic and local CS use, as discontinuation could benefit obesity-related outcomes in certain patients.
Authors
- Elisabeth F. C. van Rossum (ORCID: https://orcid.org/0000-0003-0120-4913)
- Eline S. van der Valk (ORCID: https://orcid.org/0000-0001-5134-5453)
- Mariëtte R. Boon (ORCID: https://orcid.org/0000-0002-3247-7538)
- Mostafa Mohseni (ORCID: https://orcid.org/0000-0003-0021-5477)
- Mesut Savas (ORCID: https://orcid.org/0000-0001-5223-1140)
- Maartje J B Van der Hurk
Institutions
- University Medical Center (US)
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-04-02
- DOI
- https://doi.org/10.1210/clinem/dgaf166
- Citations
- 7
- Primary Topic
- Obesity and Health Practices
- Type
- article
- Field-Weighted Citation Impact
- 14.15
Funders
- ZonMw
- Ministerie van Volksgezondheid, Welzijn en Sport
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Universitair Medisch Centrum Groningen