Associations of weight-adjusted-waist index and systemic immune-inflammatory index with sKlotho: evidence from the NHANES 2007-2016
There is a negative correlation between WWI and sKlotho, and SII may be an important mediator between WWI and sKlotho. Reducing inflammatory conditions in obese populations may increase sKlotho levels, which in turn may delay organismal aging in middle-aged and elderly people.
Authors
- Linjuan Huang (ORCID: https://orcid.org/0000-0003-0260-9920)
- Luwen Zhu (ORCID: https://orcid.org/0000-0003-4638-7004)
- Qiong Xu
- Mingming Yang (ORCID: https://orcid.org/0000-0002-4627-4184)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3389/fendo.2025.1544796
- Citations
- 2
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 2.09