Integrating single-cell sequencing and transcriptome analysis to unravel the mechanistic role of sialylation-related genes in sepsis-induced acute respiratory distress syndrome

We identified CD19 and GPR65 as key genes associated with sialylation in sepsis-induced ARDS, highlighting CD14Mono as key cell type implicated in sepsis-induced ARDS. These findings offered theoretical support for understanding the mechanism of sialylation on sepsis-induced ARDS.

Authors

Quanxing Liu (ORCID: https://orcid.org/0000-0002-6725-385X)
Yubi Huang (ORCID: https://orcid.org/0000-0003-4323-7596)
Jigang Dai (ORCID: https://orcid.org/0000-0002-3699-8138)
Hao Zhang (ORCID: https://orcid.org/0000-0003-2376-4452)
Xia Yang (ORCID: https://orcid.org/0009-0000-9682-1193)
Xiaobing Liu

Institutions

Army Medical University (CN)
Daping Hospital (CN)
Xinqiao Hospital (CN)

Publication Details

Journal: Frontiers in Immunology
Published: 2025-05-01
DOI: https://doi.org/10.3389/fimmu.2025.1528769
Citations: 3
Primary Topic: Immune cells in cancer
Type: article
Field-Weighted Citation Impact: 2.39

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article

Integrating single-cell sequencing and transcriptome analysis to unravel the mechanistic role of sialylation-related genes in sepsis-induced acute respiratory distress syndrome

Quanxing Liu, Yubi Huang, Jigang Dai, Hao Zhang et al.

May 1, 2025

3 citations

Frontiers in Immunology

Immune cells in cancer

2.39

article

Integrating single-cell sequencing and transcriptome analysis to unravel the mechanistic role of sialylation-related genes in sepsis-induced acute respiratory distress syndrome

Quanxing Liu, Yubi Huang, Jigang Dai, Hao Zhang, Xia Yang, Xiaobing Liu

May 1, 2025article en

3 citations

Abstract

We identified CD19 and GPR65 as key genes associated with sialylation in sepsis-induced ARDS, highlighting CD14Mono as key cell type implicated in sepsis-induced ARDS. These findings offered theoretical support for understanding the mechanism of sialylation on sepsis-induced ARDS.

Frontiers in ImmunologyVol. 16

Army Medical University (CN), Daping Hospital (CN), Xinqiao Hospital (CN)

Openalex Percentile: Top 12%

Immune cells in cancer

2.39

DOI Open Access PDF OpenAlex

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Integrating single-cell sequencing and transcriptome analysis to unravel the mechanistic role of sialylation-related genes in sepsis-induced acute respiratory distress syndrome — Quanxing Liu, Yubi Huang, et al. · Frontiers in Immunology (2025) | TGRS Research Map | TGRS