Sex-based estimation of biological variation in plasma-free amino acid concentrations among healthy adults
This Biological Variation Data Critical Appraisal Checklist-compliant study provides the first updated BV data for plasma FAAs. The significant variation observed in CV<sub>I</sub> estimates is hypothesized to result from differences in the metabolic regulation of essential versus non-essential amino acids. The sex-stratified indices obtained in this study will aid in the appropriate application of population-based reference intervals for plasma FAA assessment.
Authors
- Emiş Deniz Akbulut (ORCID: https://orcid.org/0000-0003-1107-9650)
- Yakup Dülgeroğlu (ORCID: https://orcid.org/0000-0003-0695-5708)
- Müjgan Ercan (ORCID: https://orcid.org/0000-0002-9291-4197)
- Şerif Ercan (ORCID: https://orcid.org/0000-0001-9034-1404)
- Esra Fırat Oğuz (ORCID: https://orcid.org/0000-0002-8147-5379)
- Ayşen Caniklioğlu (ORCID: https://orcid.org/0000-0001-8128-6044)
- Esin Avcı (ORCID: https://orcid.org/0000-0002-9173-0142)
Institutions
- Yozgat Bozok Üniversitesi (TR)
- State Hospital (GB)
- Memorial Ankara Hospital (TR)
- Yenişehir Hospital (TR)
- Başkent University Hospital (TR)
- Pamukkale University (TR)
- Afyon Kocatepe University (TR)
Publication Details
- Journal
- Journal of Mass Spectrometry and Advances in the Clinical Lab
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jmsacl.2025.04.010
- Citations
- 1
- Primary Topic
- Muscle metabolism and nutrition
- Type
- article
- Field-Weighted Citation Impact
- 1.15