Nrf2-dependent effects of CDDO-Me on bactericidal activity in macrophage infection models
The ability of CDDO-Me to regulate oxidative stress, inflammation, and bacterial clearance underscores its therapeutic potential for managing inflammatory and infectious diseases indiabetes and CKD.
Authors
- Ahmad Chehaitly (ORCID: https://orcid.org/0000-0002-5864-4429)
- Marcel Bonay (ORCID: https://orcid.org/0000-0003-1446-7456)
- Thérèse B. Deramaudt (ORCID: https://orcid.org/0000-0003-0997-1367)
Institutions
- Inserm (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologie appliquées (FR)
- Hôpital Ambroise-Paré (FR)
- Bicêtre Hospital (FR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3389/fimmu.2025.1574776
- Citations
- 1
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Institut National de la Santé et de la Recherche Médicale
- Université de Versailles Saint-Quentin-en-Yvelines