D-11 | Comparing Clinical Outcomes in Early and Delayed Mechanical Circulatory Support Among Patients With Non-ST Elevation Myocardial Infarction and Cardiogenic Shock

the relationship between the degree of change in troponin and presence of significant CAD on coronary angiograms in CKD patients.Methods: We retrospectively reviewed 50 charts of known CKD patients diagnosed with ACS who underwent coronary angiograms.Multivariate linear regression was used to examine the association between delta troponin and degree of stenosis.Significant CAD was defined as 3 70 % stenosis.Results: Mean age was 69 AE 11 years, 50% were female.60% Caucasians, 35% Black and 5% Hispanic.Most patients were CKD V with comparable cardiac risk factors including hypertension, diabetes, and hyperlipidemia.Of 50 patients, 35 had significant CAD.There was a trend towards a higher rise in troponin among patients with significant CAD (delta 0.29 ng/ml higher compared with those without significant CAD; b 0.29, CI -1.23 to 0.70, P value of 0.16).Conclusions: Our study shows that among patients with CKD presenting with ACS, there was a trend towards a higher rise in troponin among those with significant CAD compared with patients without significant CAD.Such difference may be important in risk stratifying patients and triaging them to early coronary angiography.Further studies may help clarify this association and establish troponin cutpoints.