F-102 | Finding the Bigger Leech: A Real-World Comparison of In-hospital Bleeding Risk & Hospital Utilization Between Mechanical Thrombectomy and Catheter Directed Lysis

endpoints included procedure time, thrombus volume reduction, blood loss, length of stay, and hemodynamic changes.Adverse events were reported utilizing the SIR adverse events classification system which included evaluation for major bleeding, major vascular injury, in-hospital mortality, and 30-day mortality.Results: The 16 male and 16 female patients (N32) included in the study had a mean age of 62 years old .Three massive and 29 submassive pulmonary emboli patients were treated.Technical success was achieved in 100% of patients.Mean pulmonary artery pressure reduction was 6 mmHg (p <0.005); previously 4 mmHg in the index study.Clinical improvement was noted in 100% of patients.Mean procedure time was 60.5 minutes ; 53.1 minutes in the index study.Mean fluoroscopy time was 17.8 minutes; 16.4 minutes in the index study.Average thrombus volume reduction was 90% [70-95%]; 89% in the index study.Average procedural blood loss was 122 mL [10-300mL]; 117.5 mL in the index study.Average and median hospital stay were 6.6 and 4 days respectively [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19].No confirmed major bleeding, major vascular injury, in-hospital mortality or 30-day mortality occurred.One patient had a small access site hematoma which resolved with nominal pain therapy (mild AE, Category 3 causality, self-resolved).Conclusions: This updated cohort demonstrated similar desirable outcomes compared to other studied mechanical thrombectomy devices.

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Publication Details

Journal
Journal of the Society for Cardiovascular Angiography & Interventions
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jscai.2025.103487
Primary Topic
Leech Biology and Applications
Type
article
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article

F-102 | Finding the Bigger Leech: A Real-World Comparison of In-hospital Bleeding Risk & Hospital Utilization Between Mechanical Thrombectomy and Catheter Directed Lysis

Seema Sharma Gautam, Torrey Schmidt, Vivek Verma, Sulochana Khadka et al.
Journal of the Society for Cardiovascular Angiography & Interventions
Leech Biology and Applications
article

F-102 | Finding the Bigger Leech: A Real-World Comparison of In-hospital Bleeding Risk & Hospital Utilization Between Mechanical Thrombectomy and Catheter Directed Lysis

Seema Sharma Gautam, Torrey Schmidt, Vivek Verma, Sulochana Khadka, Ashwin Mahesh
article en

Abstract

endpoints included procedure time, thrombus volume reduction, blood loss, length of stay, and hemodynamic changes.Adverse events were reported utilizing the SIR adverse events classification system which included evaluation for major bleeding, major vascular injury, in-hospital mortality, and 30-day mortality.Results: The 16 male and 16 female patients (N32) included in the study had a mean age of 62 years old .Three massive and 29 submassive pulmonary emboli patients were treated.Technical success was achieved in 100% of patients.Mean pulmonary artery pressure reduction was 6 mmHg (p <0.005); previously 4 mmHg in the index study.Clinical improvement was noted in 100% of patients.Mean procedure time was 60.5 minutes ; 53.1 minutes in the index study.Mean fluoroscopy time was 17.8 minutes; 16.4 minutes in the index study.Average thrombus volume reduction was 90% [70-95%]; 89% in the index study.Average procedural blood loss was 122 mL [10-300mL]; 117.5 mL in the index study.Average and median hospital stay were 6.6 and 4 days respectively [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19].No confirmed major bleeding, major vascular injury, in-hospital mortality or 30-day mortality occurred.One patient had a small access site hematoma which resolved with nominal pain therapy (mild AE, Category 3 causality, self-resolved).Conclusions: This updated cohort demonstrated similar desirable outcomes compared to other studied mechanical thrombectomy devices.

Journal of the Society for Cardiovascular Angiography & InterventionsVol. 4(5)
UPMC Central Pa (US), Pinnacle Clinical Research (US)
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Openalex Percentile: Top 89%
Leech Biology and Applications
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