The Standard LRINEC Scoring and Its Reliability in Prediction of Onset and Outcome of Necrotizing Fasciitis: A Five Years Retrospective Study

Necrotizing fasciitis (NF) is a rare, fast-progressing soft tissue infection primarily affecting subcutaneous and fascial tissues, with significant risks of morbidity and mortality, including limb loss or death. Early diagnosis is critical but often limited due to the cost and availability of imaging techniques like CT, MRI, and frozen section biopsy. The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scoring system, based on routine and widely accessible lab tests, can facilitate early detection and improve outcomes. Our study aims to evaluate the correlation between this scoring system and patient outcomes, including survival, the necessity for surgical intervention, and mortality in cases of NF. This retrospective study analysed patients admitted to a tertiary care center with NF, myonecrosis, cellulitis, or Fournier’s gangrene between September 2018 and September 2023. Case records were reviewed to calculate LRINEC scores, which were compared with treatment outcomes. Patients were categorized into two groups: Survivors and non-survivors. The average LRINEC score was 3.7 ± 1.38 in the survivor group and 8.1 ± 3.2 in the non-survivor group, with a statistically significant difference ( P = .003). The findings highlight that higher LRINEC scores are associated with poor outcomes, confirming its usefulness as a diagnostic and prognostic tool. By identifying at-risk patients early, clinicians can initiate timely and appropriate interventions, potentially reducing mortality and improving patient care.