VARIANTS OF THE CLINICAL COURSE OF DIABETIC FOOT SYNDROME

The aim of the study was to analyse the variants of the clinical course of diabetic foot syndrome, to determine the main features of its progression and key predictors of complications. The prevalence of diabetes mellitus (DM) continues to increase all over the world, which in turn leads to an increase in the incidence of diabetic foot syndrome (DFS). DM is one of the main causes of chronic diseases, and the DFS is a main cause of non-traumatic amputation of the limbs throughout the world. Currently, 382 million people suffered. WHO predicts that by 2035, the number of registered patients with diabetes in the world will increase to 592 million. DFS is the most dangerous surgical complication of type 2 diabetes mellitus. According to international studies, the DFS is the reason for the hospitalization of each fourth patient with diabetes, each seventh undergoes a high amputation of the limb, with a five-year survival after amputation of the limb, according to various data, does not exceed half of the cases. The diabetic foot syndrome associates with significant complications and morbidity, requiring frequent consultations by physicians of various specialties, daily wound care, antimicrobial therapy, surgical intervention, accompanied by high costs of health care. Based on the analysed literature of foreign authors, the main methods of classification of the clinical course of complications of chronic diabetes mellitus were determined, information was collected on the target groups of patients with the presence of initial and long-term forms of purulent-necrotic changes in the wound process. In order to control possible complications, the dynamics of pain syndrome, local signs of inflammation, the presence of discharge and the features of ischaemic and mixed forms of diabetic foot syndrome were studied. Predictors that can lead to the formation of Charcot's neuroarthropathy and further development of the infectious process in the wound were identified.