Effect of cyclophospamide, doxorubicin, vincristine and prednisone/prednisolone (CHOP) chemotherapy regimens on left ventricular systolic function and cardiac structural abnormalities in non-Hodgkin lymphoma patients
The CHOP regimen poses significant risks of subclinical cardiac dysfunction and structural abnormalities in NHL patients, with cumulative doxorubicin dosage being a key contributor. Early detection using sensitive biomarkers like GLS and NT-proBNP is crucial for identifying cardiotoxicity and enabling timely interventions.
Authors
- Imanita Septianda
- Ami Ashariati (ORCID: https://orcid.org/0000-0003-0508-4496)
- Fatimah Zahra (ORCID: https://orcid.org/0000-0001-7806-2007)
- Muhamad Robiul Fuadi
- Mochamad Yusuf Alsagaff (ORCID: https://orcid.org/0000-0003-2194-6850)
- Budi Susetyo Pikir (ORCID: https://orcid.org/0000-0003-0705-9462)
Institutions
- Universitas Airlangga (ID)
- Universitas Dr. Soetomo (ID)
Publication Details
- Journal
- Journal of the Egyptian National Cancer Institute
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s43046-025-00288-w
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.00