Early diagnosis and survival outcomes in silicosis: a retrospective cohort study of 11,809 patients in Guangdong Province, China (1956–2020)
This study demonstrates that early diagnosis significantly prolongs survival in silicosis patients, with advanced stages correlating with exponentially higher mortality. The findings underscore the urgent need for systematic early screening, such as high-resolution CT, and stricter occupational health policies to reduce silica exposure. Despite limitations, including unmeasured confounders like smoking status, this research provides critical evidence to inform global strategies for mitigating silicosis through timely detection and workplace safety reforms.
Authors
- Qiaoli Wei
- Chun-yue Fan
- Lin Wu (ORCID: https://orcid.org/0000-0003-3728-8418)
- Lihua Xia (ORCID: https://orcid.org/0000-0001-8735-1679)
- Jiawen Huang (ORCID: https://orcid.org/0000-0002-6443-2203)
- Xudong Li (ORCID: https://orcid.org/0000-0003-0535-1793)
- Yuhao Wang (ORCID: https://orcid.org/0000-0002-3174-8922)
- Jingjing Chen (ORCID: https://orcid.org/0000-0003-4252-9255)
- Shijie Hu
- Weihui Liang
Institutions
- Sun Yat-sen University (CN)
- Guangzhou Center for Disease Control and Prevention (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3389/fpubh.2025.1587161
- Citations
- 2
- Primary Topic
- Occupational and environmental lung diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Sun Yat-sen University
- Natural Science Foundation of Guangdong Province