Global Results From the Optimize PRO Study: Standardized TAVR Technique and Care Pathway
The Optimize PRO study demonstrated low rates of new permanent pacemaker implantation and no moderate to severe aortic regurgitation after TAVR with Evolut PRO/PRO+ using COT and perioperative protocols in a global cohort of severe aortic stenosis patients. Best practices resulted in consistent implantation depth and low complication rates.
Authors
- Steven J. Yakubov (ORCID: https://orcid.org/0000-0002-0952-7509)
- Diego Maffeo
- M. Yudi (ORCID: https://orcid.org/0000-0002-3706-4150)
- Ibrahim Sultan (ORCID: https://orcid.org/0000-0002-1737-4012)
- Douglas Fraser (ORCID: https://orcid.org/0000-0001-5313-1483)
- Tamim Nazif (ORCID: https://orcid.org/0000-0003-1239-2489)
- Robert Gooley
- Hemal Gada
- César Morı́s (ORCID: https://orcid.org/0000-0002-2871-190X)
- Blake Gardner
- Suneet Mittal (ORCID: https://orcid.org/0000-0002-8003-7254)
- Gerald Yong (ORCID: https://orcid.org/0000-0002-5962-9300)
- Kendra J. Grubb (ORCID: https://orcid.org/0000-0002-1369-5521)
- Josep Rodés‐Cabau (ORCID: https://orcid.org/0000-0001-8237-7095)
- David H. Lorenz (ORCID: https://orcid.org/0000-0002-7451-099X)
- Nainesh Patel (ORCID: https://orcid.org/0000-0001-5620-4000)
- Lang Lin
- Danny Dvir
- Darren Mylotte (ORCID: https://orcid.org/0000-0001-7824-2577)
- Stanley Chetcuti
- Carlo Trani (ORCID: https://orcid.org/0000-0001-9777-013X)
- Deepak Talreja
- Joshua D. Rovin (ORCID: https://orcid.org/0000-0001-9023-4422)
- Emmanuel Teíger (ORCID: https://orcid.org/0000-0001-7515-4344)
- Brian S. Schwartz (ORCID: https://orcid.org/0000-0002-0739-9865)
- Yu Jung Yeh
- John Wang (ORCID: https://orcid.org/0000-0002-3959-2328)
- James E. Harvey
- Zubair Jafar
- Paul Mahoney
- Jan Van der Heyden
- Ramzi F. Khalil
- Katie Flor
Institutions
- Università Cattolica del Sacro Cuore (IT)
- OhioHealth (US)
- York Hospital (GB)
- NewYork–Presbyterian Hospital (US)
- Emory University (US)
- East Carolina University (US)
- University of Michigan (US)
- Columbia University Irving Medical Center (US)
- Riverside Methodist Hospital (US)
- Morton Plant Hospital (US)
- Valley Hospital (US)
- Allegheny General Hospital (US)
- Austin Hospital (AU)
- Fiona Stanley Hospital (AU)
- UPMC Central Pa (US)
- York General Hospital (US)
- Intermountain St. George Regional Hospital (US)
- Manchester Royal Infirmary (GB)
- Shaare Zedek Medical Center (IL)
- Kettering Medical Center (US)
- Agostino Gemelli University Polyclinic (IT)
- MedStar Union Memorial Hospital (US)
- University Hospital Galway (IE)
- Medtronic (Ireland) (IE)
- St. Vincent's Medical Center (US)
- Medtronic (United States) (US)
- Sentara Heart Hospital (US)
- AZ Sint-Jan (BE)
- Hôpitaux Universitaires Henri-Mondor (FR)
- Lehigh Valley Hospital (US)
- Hospital Universitario Central de Asturias (ES)
- University of Pittsburgh Medical Center (US)
- Vassar Brothers Medical Center (US)
- Fondazione Poliambulanza Istituto Ospedaliero (IT)
- Australian Centre for Heart Health (AU)
- Université Laval (CA)
- Monash Institute of Medical Research (AU)
Publication Details
- Journal
- Journal of the Society for Cardiovascular Angiography & Interventions
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jscai.2025.103515
- Citations
- 3
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- Abbott Laboratories
- Medtronic
- Medtronic