Role of Denosumab in Patients with Intermediate Spinal Instability Neoplastic Score (SINS)
In this study, denosumab lowered the rate of conversion to surgery in patients with impending instability (intermediate SINS) due to spinal metastasis. Patients who received denosumab treatment showed significant improvements in the SINS and HU for their metastatic spinal lesions.
Authors
- Sung Taeck Kim (ORCID: https://orcid.org/0000-0002-8403-814X)
- JunYeop Lee (ORCID: https://orcid.org/0000-0002-8257-7959)
- Hyoungmin Kim (ORCID: https://orcid.org/0000-0002-4500-9653)
- Seonpyo Jang (ORCID: https://orcid.org/0009-0003-0973-6276)
- Sam Yeol Chang (ORCID: https://orcid.org/0000-0003-4152-687X)
- Bong‐Soon Chang (ORCID: https://orcid.org/0000-0002-8992-2559)
Institutions
- Seoul National University Hospital (KR)
Publication Details
- Journal
- Cancers
- Published
- 2025-05-01
- DOI
- https://doi.org/10.3390/cancers17091539
- Citations
- 1
- Primary Topic
- Management of metastatic bone disease
- Type
- article
- Field-Weighted Citation Impact
- 2.01