Prognostic role and tumor-suppressive effects of CADM family members and the potential molecular mechanisms of CADM1 in neuroblastoma
Decreased expression of CADM1 and CADM3 was significantly associated with poor outcomes in neuroblastoma. CADM1 may suppress neuroblastoma cell proliferation and migration through regulating the phosphorylation of GSK-3β.
Authors
- Jigang Yang (ORCID: https://orcid.org/0000-0002-0538-7676)
- Jun Liu (ORCID: https://orcid.org/0000-0001-9021-4632)
- Lingling Zheng (ORCID: https://orcid.org/0000-0001-7333-2768)
- Ying Kan (ORCID: https://orcid.org/0000-0001-8115-6071)
- Wei Wang (ORCID: https://orcid.org/0009-0003-7539-9394)
- Mingyu Zhang (ORCID: https://orcid.org/0000-0001-7907-3971)
- Yu Wang (ORCID: https://orcid.org/0000-0001-7706-2160)
Institutions
- Capital Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1007/s12672-025-02350-4
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Beijing Municipality