Autologous umbilical cord blood mononuclear cell therapy for hypoplastic left heart syndrome: a nonrandomized control trial of the efficacy and safety of intramyocardial injections
Intramyocardial injections of autologous UCB-MNC products into the right ventricular myocardium during stage II palliation surgery failed to enhance cardiac function in patients with hypoplastic left heart syndrome. REGISTERED ON CLINICALTRIALS.GOV: Registered on ClinicalTrials.gov (NCT03779711) on 12/04/2018; URL: https://clinicaltrials.gov/ct2/show/NCT0377971 .
Authors
- Waldemar F. Carlo (ORCID: https://orcid.org/0000-0002-5460-9079)
- James Jaggers (ORCID: https://orcid.org/0000-0003-2934-3368)
- Clinton E. Hagen
- Joseph William Rossano (ORCID: https://orcid.org/0000-0002-8284-0673)
- Drew K. Seisler
- Susana Cantero Peral
- David L.S. Morales (ORCID: https://orcid.org/0000-0002-7512-1777)
- Carlos Gallego-Navarro (ORCID: https://orcid.org/0000-0003-3937-9102)
- M. Yasir Qureshi (ORCID: https://orcid.org/0000-0002-9898-2318)
- Harold M. Burkhart (ORCID: https://orcid.org/0000-0002-2766-0418)
- Timothy J. Nelson
Institutions
- Cincinnati Children's Hospital Medical Center (US)
- Mayo Clinic (US)
- Children's Hospital of Philadelphia (US)
- University of Alabama at Birmingham (US)
- Children's Hospital Colorado (US)
- Pediatric Nephrology of Alabama (US)
- University of Minnesota Rochester (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- University of Oklahoma Health Sciences Center (US)
- University of Colorado Denver (US)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s13287-025-04316-3
- Citations
- 3
- Primary Topic
- Congenital Heart Disease Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.06