Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China

This study represents the first investigation elucidating the role of genetic variations in the METTL4 gene and their influence on susceptibility to severe pneumonia in pediatric populations. METTL4 is identified as a novel predisposing gene for severe pneumonia and a potential therapeutic target. Further research is warranted to validate this correlation and to comprehensively elucidate the biological role of the METTL4 gene in severe pneumonia.

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Publication Details

Journal
BMC Genomic Data
Published
2025-05-01
DOI
https://doi.org/10.1186/s12863-025-01306-5
Primary Topic
Pneumonia and Respiratory Infections
Type
article
Field-Weighted Citation Impact
0.00

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article

Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China

Liuheyi Ma, Xiaoyu Zuo, Bingtai Lu, Yuxia Zhang
BMC Genomic Data
Pneumonia and Respiratory Infections
article

Correlation of METTL4 genetic variants and severe pneumonia pediatric patients in Southern China

Liuheyi Ma, Xiaoyu Zuo, Bingtai Lu, Yuxia Zhang
article en

Abstract

This study represents the first investigation elucidating the role of genetic variations in the METTL4 gene and their influence on susceptibility to severe pneumonia in pediatric populations. METTL4 is identified as a novel predisposing gene for severe pneumonia and a potential therapeutic target. Further research is warranted to validate this correlation and to comprehensively elucidate the biological role of the METTL4 gene in severe pneumonia.

BMC Genomic DataVol. 26(1)
South China University of Technology (CN)
National Natural Science Foundation of China
Openalex Percentile: Top 87%
Pneumonia and Respiratory Infections
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