Unraveling breast cancer response to neoadjuvant chemotherapy through integrated genomic, transcriptomic, and circulating tumor DNA analysis
Our comprehensive multi-omics analysis identified promising biomarkers predictive of treatment response and survival in BC patients receiving NAC followed by surgery. These findings underscore the importance of early tumor assessment for improved patient stratification and prognostication.
Authors
- Yueyin Pan (ORCID: https://orcid.org/0000-0003-0532-5368)
- Jinguo Zhang (ORCID: https://orcid.org/0000-0001-9952-9307)
- Fufeng Wang (ORCID: https://orcid.org/0000-0002-8933-4909)
- Wenhui Wei
- Qiuxiang Ou (ORCID: https://orcid.org/0000-0002-2961-2057)
- Menghao Dong
- Xinghua Han (ORCID: https://orcid.org/0000-0002-0632-6955)
- Nannan Lu (ORCID: https://orcid.org/0000-0001-8164-7751)
- Xiaopeng Ma
- Jinnan Wang (ORCID: https://orcid.org/0000-0002-2882-914X)
- Hua Bao (ORCID: https://orcid.org/0000-0001-5774-8755)
- Song Wang (ORCID: https://orcid.org/0000-0002-8351-6656)
- Ziming Wang (ORCID: https://orcid.org/0000-0002-2440-9412)
- Jian Chen (ORCID: https://orcid.org/0000-0003-4560-1873)
- Benjie Shan
Institutions
- University of Science and Technology of China (CN)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1186/s13058-025-02026-5
- Citations
- 5
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- National Natural Science Foundation of China