Pediatric Scar Management Using Tangential Excision With Intralesional Injections and Laser-Assisted 5-Fluorouracil Delivery
Tangential excision with 5-FU monotherapy demonstrated lower scar height and improved overall scar quality, further solidifying the benefits of 5-FU. CO2 laser-assisted 5-FU delivery had similar complication rates as the other studied modalities. This pediatric study had no systemic complications and overall similar complication rates compared to adult studies. This study demonstrates the utility of 5-FU in pediatric scar therapy and provides data regarding novel approaches to difficult pediatric scar management.
Authors
- Amanda A. Gosman (ORCID: https://orcid.org/0000-0002-6782-9302)
- Samuel Lance (ORCID: https://orcid.org/0000-0002-5186-2677)
- Cyril Harfouche (ORCID: https://orcid.org/0009-0000-8835-6594)
- Ruby H.N. Nguyen (ORCID: https://orcid.org/0000-0002-6598-8457)
- Miriam Becker (ORCID: https://orcid.org/0009-0006-4735-4035)
- Robert L. Clark (ORCID: https://orcid.org/0009-0002-7030-1741)
- Kelli Lopes
Institutions
- University of California San Diego (US)
- Baylor Scott & White Medical Center - Temple (US)
- Carilion Clinic (US)
- Virginia Tech (US)
Publication Details
- Journal
- Annals of Plastic Surgery
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1097/sap.0000000000004207
- Citations
- 1
- Primary Topic
- Dermatologic Treatments and Research
- Type
- article
- Field-Weighted Citation Impact
- 2.00